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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce0c2941bb2f12f02ff91015fd71c7c81f7ddc74266d9690e1afb74400f0eec1' 
  AND token = 'O6knmCRUqSZhZr0eKq7j1eTnljLwchQeYNLdLiov5tY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}