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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8841c4a3bc0a71792768fc29ed23a13a235a79b7a8fc9a6725b9a658616f38f0' 
  AND token = 'MJsPfIuJbyrFUCkFW7CTlLzCt+OY22oUlIk75ohQ6jY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}