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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a589e9c23ba105b97921cc6900759654e2f59c13a078d2a9d4cc8bb09a5cc352' 
  AND token = 'zxfC+3xpysqQ2Gpb/+fvEWDZATNOsKq8g+7GjtbqY8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}