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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7aeb729c5563063c700234a37417fe6d902703b2a63499c47ad619516074e9ab' 
  AND token = 'LCtDa23pr0qXTvO+QKEcO6ZJyVHv/HOyZoe+U2J2cSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}