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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '290a8bd055c668161a26afe95ece617ca60c5b854edc20feb3b1a54bceae8f06' 
  AND token = 's2ZIT7qxx/QWhsr9I29aguhXKfe0yBriZc4456anz7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}