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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ebb807ca8141e08e4c813a67df3ccd8959e1c2d38d951d29b79a723c398295d8' 
  AND token = 'a+/qsy0J+jFYxsdoLB81YQ7DO9GHUIk8SYUpxrZGwvY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}