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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45e380d24e0afb900a6f928a4a6dfd01a77730d884844b1a48963b87d0d075eb' 
  AND token = 'MH8OSDR85hU4Wo4QIhXSxPx7XSXskDo3hPKBJGOoYks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}