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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2b235e10cb71f02368d6ec2bf22518625cdb5c925f6cf4e0d106fcc78be86c5' 
  AND token = 'qyobGZIzAXKrv1bFAiIM+9fULyJdKS8Okp+n0xXJUMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}