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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bbb1f148a8a539170d13932cab490350a1544bd8da500c453b8a5f3b5e73c80c' 
  AND token = 'U2+1Wl+SWBHODJtM1YgkRY2ijXHQa48kg3Rzh2hvoW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}