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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '533461b6798208edd809e1d57359ba67eb4bb74f55bfd1827dc50ae746920e4f' 
  AND token = 'LsZKf7/fbLuYE1d8UBhVwMyqAyKwC9NKA2zJTyaM6rA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}