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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d510385e375dcf4197b4a6dc0da712d553aea19a2161dbe10e24e8dc6918c1f' 
  AND token = 'A62RAS++6IvrSmGF6wtouTj0HfNQONaumHJKWGZwpTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}