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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a01d3ee9faa7e9a2fbf477685ccac6af84ddcf6f4767ce99721be23ba9a69335' 
  AND token = 'DnAjy47a+XsdMB/9k4h2uNrnRRMHSNlZFyLNm3RqzkE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}