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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d00e2fcdd24bdadac647fa6332f207aae2d79830e06e2f6c00ee268be4e2385' 
  AND token = 'jUxgjEt/35AptyMY6YhnNld44RgC5tWmnExvpHMVf4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}