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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '84c1ab2154c20729a7b2b1d5485069b01c4c2d3bba6dfd3ddef90a9b51c2541a' 
  AND token = 'f7SSmj+1dzCQp1wgepuJcrYg34bCgAdap0YwvUDvHEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}