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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3dc4d05e9b025814ec266caac00cd53fd663c2a7c30ecfc475ec2ba91e78c247' 
  AND token = 'gk52Qezw6K6jXpuJktu5wrJYGkKlLsUrybtCPU6iy+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}