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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42ae5a88f3818c2cdbef602a25202b6788e4c47bb7e004ddd1a33e3a91edc7c9' 
  AND token = 'Z3MX8geGJCjYqDzCRR03XSwIai0gk9SB7mm3Z6DBH+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}