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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a69e6c4cabf8326d412b7131eccbf79253f077e000a7ba5ef509b33fdebc64b' 
  AND token = 'CrdNc729mRw9j8+vO+6JEZfeCS745C90FdnLcO8KPsw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}