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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85112c8ae53bd6c0dfd3a694bdd156c7344e55aebeea45dcb4356ee396a8b61c' 
  AND token = 'DOH0VH1mechqJeicgkY1gjzDF8j++lou1Ds0T5l4BQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}