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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f21e9b228bb347df6af39201c8a3fcdaf88c3545b3e0f5ca6cf004a906339ee' 
  AND token = 'SjQoUO8DmCECL7NXIPMQDBwhGHT1ptkZhG+kMsY3sIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}