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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '408434af9a80d0bdc94443e373e5df02f38ffc10d9f4b0113deb8eb7ceae04f9' 
  AND token = 'VCPpqzcMFZ7sXfyTM/mHWd1x/xrMdbPwO2gdfTp+XAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}