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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95a86547dd239ef5d9145e9281aec709e3e7a86896e8dc9c1bfe619f5320b4cd' 
  AND token = 'XyF6BoDxUG9FpNY4l5I5jf7TouYq2zsDQ18CIOfr3FI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}