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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3763490b36fe2c28093fdfb96cbe3034bd358d66619af0e6a3502aeb1b40caca' 
  AND token = '5JG2NFG+ysIE4cttKWFTSDvwf1u5+9lYrRB5D7WLu5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}