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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04a5d6d3cc7e9b266ad250c432a4156efdfadb9f7af199d2b1113351996c5b13' 
  AND token = 'HT4pHx8fhfJdjiWdjun8Q3D4duN8T9rZvHJlOmr2JvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}