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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fb8422935eb3dad620471357d46c6a6c82c63a1e91fcee79193ea7b78f7b6ce' 
  AND token = 'QPqxRPMNeoGHV91+513dxJIGJCH4/Zjj2FQ8Zphy97M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}