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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b48f087d9e13bd7dba732729a3b7f131c29f7c0392eaf6e81aea95c2f6d67fe' 
  AND token = '+T/D+fZYs2dKKcWaNMYy4smzkGoRt726YvURXD/wvqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}