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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff5017aec6d95d01268499b9fe79f01f06796746d4e956f216c871c335c5e8cd' 
  AND token = 'gEdhCizqv62g2ZC1+/MS2vwzvdOCpCr8M70qOiJLGyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}