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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b86b9fc787f97f37204fcf98a37a9a4dd6e648f40144b81f12d9f4635d2fbec6' 
  AND token = 'YUAe92Th5X8VTQIDsniUuaAVSCvZyXAl4RN5xrOYhqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}