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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac1c1f313e8fb27040cfb104f68f17de5df12749bd664af11bd268c5d3446632' 
  AND token = 'o/EhtUNC7HdEM/06t6jhW5rEy1YzfJOsgO8HBSGgzz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}