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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ce3170a64104d0d8bd946e7776b93688376127fc4ff8cbc85147a378c0196ae' 
  AND token = 'l9e7NPBi6GWlFwh+M7cdaWMpUGJfCfJFQo5zyLga69A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}