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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '746d1614ea5acc913771de41a376f7492163f88a4cf64e8fb30f4fd4b3535233' 
  AND token = 'Y0Nm7hGwCLxqGpnpA9qVq0N0EMtN/aLvXl1rIabPL5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}