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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67d018cf2ae25de562e2a20555d00ee62d723c7985507ca74ea0a2e583d01d05' 
  AND token = 'Ssg1/QLaIXBp2FvFMFRSTSZY2FzljGBo+jR5CC8sCaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}