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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f086f6d6522dc83535b170820fb6f5bbaa4e1b3dd364ce736aec467611c33c7' 
  AND token = 'K23LUGG2Qtn+Q8MrEcA8aHsILWgw+gDHOaO+9wulqLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}