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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec07cf619bf03de2f64e9250f672687aa06f6a09019d97d0f555a15e5aaefde4' 
  AND token = '0yPeDz1jaTwDDNAKfttA74rZirYrIVjvSFOt1WAB5wM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}