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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '821f1b1c7fb341e056a343e96d709ca87bb81bb82e49cbfee24ac2d77959701e' 
  AND token = '50X4li8MnkwjdRzE0U6vS22BjF2a6rmQfNSe8clwbLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}