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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06e625a8638a398c4b8ce2c73fa32f2b41dbee8d4c4a954d95d5c81f6cd08fbb' 
  AND token = 'vFpnC6f2JqX3+h8QmXViAy3ZFHnAWD1rSdp4a84UTz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}