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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4fa6bcb1de8c7b5683cb898648bb144b5cf1aeefdc44f57d8f2604723affa5b' 
  AND token = 'HYq9qigc4S+OVif0OvH1CUfjy+U5TsWN8G69xAHQ1tw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}