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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7579feb2c9f7a1099b0177e0322dd4d9b7a66ba536a36102d204864c2d194e7' 
  AND token = 'CuGSRdX5jwFs/LCMVNqzxAfheiX4Sr7TDynIfkfZFsk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}