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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1285ea3c1d3c730a0d15ffe954b1a67a34b4ffd53b34be200bf10f3ca279c9c0' 
  AND token = 'h/0bnn/7pfH2mBSmy9QIaJK6F6fXWFcdKc3NTi3bTQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}