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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd18396bae37b71eb8fc42e830772743980f6c5d20e1f6fdddd2063a709d2266a' 
  AND token = 'QgV+l2wALXvx4CaN+ENj75o4A/L6Lhum+YEstysVY1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}