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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '065a95e19867472c37c1b44d0aa98c92471a5b3d9ee4da0339079d07ecaf20e7' 
  AND token = 'lZLzPICZusY2Q3+O7lbJI3FyhnLqDUKAasFlIW+tM6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}