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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06a6e4783cb033552ee693001d9dd6a05e5f39a8bc1e73e80cb998b9825abfc6' 
  AND token = 'esUPWvTb+T8RE3waC+Fq6L10qe8ABG8+SHWUiImFUc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}