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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4347c5e0f152f3d410a85b63933b60e91c439b9a80772b37af112bc6d2d65e06' 
  AND token = '5SkRXVeoNIKB52A+87EQ5tXSSiUpmGg2A25Ea7MzhC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}