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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfcaa11acc9868abf921b33f2305dd076f44265314dd8e7f785c80c82d78cd7a' 
  AND token = 'ZSg+KyD8ytl//ycHsU3YQxwamNRymRIn1uUqBAq5fhM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}