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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c296a595ca7b7c3599bad30d777e0d50e0b4f22f755823482ac5adfebc4b548' 
  AND token = 'WrO2kp8eNK6F4KvPz/9jvDZ+E282K/rn0cbi/rY/GFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}