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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b648a8c8643c3a724cc2698a59dd5263c33d056c901f45368fdb76d409241c2' 
  AND token = '7eQY/FnQJ9LUhdPzyEHCZGMYRdctIo0hnPt7hOHY1mA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}