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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef7768c93bd007840982d8d37fa04225f943297c2eb11f38009696b20a8ea238' 
  AND token = 'Cu7nHCszWyEoTF0Qn6ji9DWOrZd2fQzXgorNzjTlFVo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}