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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80e9e4bf3609ac29a027fd6696e1306e322094893d87c2d27b6495ff0e50b325' 
  AND token = 'aZSz4LgDHEv2UUrBH/zGfIEz+5Hmpk3/D8YAuetCnSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}