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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e61e613fec9357e7edc198009d3c00dff9242c8537aae845f79466f77a596c9' 
  AND token = 'YVDNbZAhP8geNpCN6FuuSpIMBxz2vaqWB0Hzf8rrEqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}