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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4349bacf022cb9cda13a600ed17f8457c208180cc8d9cd95e3c00314e266189e' 
  AND token = 'xHo72EJR95aYN2nRPmk4Oot74YJq4NA5zQ9c/bKzjDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}