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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '428250e6f99e973c22867c6001d5bb079adfae89be69d52c6d9743a06c84d821' 
  AND token = 'RpWReFVLAnJTyn4sOuUyUYro6jJ+ediHJBxlAL0Zj0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}